Preclinical

Enclosure

Dimensions (W x D x H)

72 cm x 77 cm x 77 cm (28.0 in. x 30.0 in. x 30.0 in.)

Weight (maximum)

110 kg (240 lbs)

General description

Light-tight enclosure with built-in computer system, status lights, and animal handling controls, as well as integrated illumination, detection, and scanning subassemblies.

Installation

Tabletop

Noise level

< 55 dB

Operating conditions
   Temperature
   Acceptable temperature fluctuations
   Relative humidity
   Atmospheric pressure

   20°C to 26°C
   < 2°C change in 15 minutes
   20% to 75% (recommended)
   70 kPa to 106 kPa

Power requirements
   North America
   European Union
   China
   Japan

   115 VAC ± 10% (protective earth), 60 Hz
   230 VAC ± 10% (protective earth), 50 Hz
   220 VAC ± 10% (protective earth), 50 Hz
   100 VAC ± 10% (protective earth), 50/60 Hz

Power consumption

300 VA

Transportation and storage
   Temperature
   Relative humidity
   Altitude

   5°C to 30°C
   Up to 95%
   Up to 40,000 ft (12 192 m)

Product Classification

Electrical classification

Class 1 (Electrical – IEC 61010-1)

Electromagnetic compatibility

Class A, Group 1 (EMC – CISPR 11)

Laser classification

Laser Class 1 Equipment (Laser – IEC 60825-1)

Illumination System

Number of lasers

Between 1 and 4 internal lasers

TD illumination source
   Available wavelengths

Pulsed laser diode
   470 nm (± 5 nm)
   635 nm (- 5 nm / + 3 nm)
   665 nm (± 5 nm)
   735 nm (± 5 nm)
   785 nm (- 10 nm / + 0 nm)

Laser pulse repetition rates
   For laser wavelengths in the range of 630 to 900 nm

   For laser wavelengths less than 630 nm

   2.5, 5, 10, 20, 40, and 80 MHz ± 1% (standard calibrations at 20 and 80 MHz)
   2.5, 5, 10, 20, and 40 MHz ± 1% (standard calibrations at 20 and 40 MHz)

CW illumination source
   Available wavelengths

CW laser diode
   532 nm (± 5 nm)

Maximum power (on the specimen table)
   470 nm pulsed laser
   635 nm pulsed laser
   670 nm pulsed laser
   735 nm pulsed laser
   785 nm pulsed laser
   532 nm CW laser

   0.33 mW
   1.00 mW
   1.00 mW
   1.00 mW
   1.00 mW
   10.0 to 20.0 mW

Profilometry Measurement

Principle of operation

Optical triangulation

Scan area (W x D x H)

190 mm x 100 mm x 50 mm

Laser wavelength

670 nm ± 20 nm

Maximum power (on the specimen table)

15.0 mW

Profilometry camera

See CCD Camera for a description of the live view/profilometry camera

Detection System

Principle of operation

Time-correlated single photon counting system

Enhanced dynamic range and sensitivity

˜ 70 dB, (equivalent to > 22 Bits CCD)

Fluorescence filters

Selectable from eight-position filter wheel
See Laser Kits for descriptions of the fluorescence filters

Scanning System

Principle of operation

3D raster scanning

Positioning assembly
   Resolution

X-Y-Z translation stage
   0.01 mm in X, Y, and Z axes

Maximum can area (W x D x H)

190 mm x 100 mm x 50 mm

Region of interest
   Size
   Types
   Scan step

   Any size ROI within maximum scan area
   Full specimen, rectangle, polygon, line, point
   Selectable between 0.5 and 3.0 mm

CCD camera
   Field of view (W x D)
   Alignment resolution
   Alignment accuracy

Provides live view and profilometry measurements
   250 mm x 150 mm
   < 0.1 mm
   < 0.25 mm

Animal Handling

Animal comfort
   Bed types
   Box types

Heated platform for animal imaging beds and boxes
   Standard single-mouse, five-mouse, optical-CT fusion
   Isolation

Temperature monitoring
   Monitoring range
   Control range
   Control accuracy

   15°C and 45°C
   28°C to 42°C
   ± 1°C

Specimen monitoring
   Movement detection
   Vital signs

   Stops measurements automatically if a significant animal position change is detected
   Customizable

Inhalation anesthesia
   Enclosure ports
   Bed types with integrated nose cones

   For isoflurane and oxygen
   Standard single-mouse, five-mouse, optical-CT fusion

Integrated Computer System

CPU
   Primary memory (RAM)
   Secondary memory (HDD)

Pentium 4, 2.6 GHz or higher
   ≥ 2 GB
   ≥ 100 GB

USB data rate

Hi-speed USB 2.0

Graphic interface memory

256 MB unified memory or more

Sound interface output mode

Stereo 5.1 or better (standard mono speaker provided)

Optical drive
   Type
   Read speed
   Write speed
   Rewrite speed
   Disc loading

DVD writer
   ±RW
   CD(24x), DVD(8x) or faster
   CD(24x), DVD±R(8x) or faster
   CD(24x), DVD±RW(4x) or faster
   Slot, vertical

Monitor type
   Diagonal size
   Maximum resolution
   Maximum SYNC rate
   Color

Flat panel display, TFT active matrix
   19 in. or more
   1600 x 1280 or more
   75 Hz x 80 KHz (V x H)
   Black

USB keyboard

Standard English keyboard with numerical keypad, black

USB mouse

Optical three-button mouse with scroll wheel, black

Enclosure Interface Panel

Monitor interface port

DB 15 HD connector

Monitor power outlet port

C13 power outlet

Keyboard interface port

USB 2.0

Mouse interface port

USB 2.0

Network interface port

8P8C connector (1000Base-T Cat6, RJ-45 compatible)

Accessible USB ports

2 or more

External laser ports
   Laser optical port
   Laser interlock port
   Communication port
   Synchronization port
   Laser control port

   FC (female) connector
   Miniature interlock (male) connector
   USB 2.0
   SMA (female) connector
   DB-9 connector

System Software

Operating system

Microsoft Windows XP Professional with SP2 or later

Application software
   OptiScan acquisition software
   OptiView analysis software
   OptiView 3D Reconstruction (optional)
   OptiView CT-Fusion (optional)

   OPTIX-SCAN, version x-xx-xx
   OPTIX-OVIEW, version x-xx-xx
   OPTIX-OVIEW-3D, version x-xx-xx
   OPTIX-OVIEW-CT, version x-xx-xx

Keys features

Automated data acquisition and calibration
Built-in tests that support self-diagnostics, including laser power levels
Automatic naming and archiving of results data

Number of animals

Up to 5 simultaneously with the five-mouse scanning bed

Specimen types

In vivo, ex vivo, microplate, bioluminescence

Scan types

Full quantitative and intensity